ASCRS 2013 poster Intermediate Results of WCCA RETROPRESS Study: Compression Anastomosis Is Associated With a Low Rate of Anastomotic Leakage
Recent Data - Compression Anastomosis for Low Anterior Resection (LAR)
Low Anterior Resection (LAR) Leakage & Mortality: Literature Analysis Compared to COMPRES Results
1,180 patients, 362/1180 LAR procedures in 16 countries (167 medical centers)
- Low leakage rate of 3.2 %; 3.2% open (17/535) and 3.2% laparoscopic procedures (21/645)
- Very low leakage rate for LAR 1.9% (7/362)
- Compression anastomosis for LAR cases may lead to decreased anastomotic complications
Masoomi H, Luo R, Mills S, Carmichael JC, Senagore AJ, Stamos MJ. Compression anastomosis ring device in colorectal anastomosis: a review of 1,180 patients. Am J Surg. 2013 April;205(4):447-451. doi:10.1016/j.amjsurg.2012.03.013. Epub 03 Jan 2013.
266 patients, 98/266 LAR procedures in 13 medical centers
- Low leakage rate for LAR - 4% (95% C.I. 0.0% - 8.0%)
- overall including leaks, abscess, fistula
- 97.4% rated the device very easy and easy to use
- No device-related mortality
- Majority of patients did not notice excretion
D'Hoore A, Cohen S, Albert M, Herbst F, Senagore A, Stamos MJ, Pahlman L, Wexner SD. COMPRES final results: nitinol compression anastomosis results in a much lower than expected rate of anastomotic leak in low anterior resection (LAR). Poster presented at: Annual Scientific Meeting of the American Society of Colorectal Surgeons (ASCRS); June 2-6, 2012; San Antonio, TX.
“Compression anastomotic healing was associated with less inflammation, scarring, and foreign body reactions as compared to stapled anastomoses.”View PDF
Berho M, Fleshman JW, Wexner SD, Anug AM, Pelled D. Histopathological advantages of compression ring anastomosis healing as compared to stapled anastomosis in a porcine model: a blinded comparative study. Poster presented at: Annual Scientific Meeting of the American Society of Colorectal Surgeons (ASCRS); June 2-6, 2012; San Antonio, TX.
There are over 50 peer-reviewed publications on novoGI’s clinically proven compression anastomosis technology. See Peer-review Library and learn more.
*LAR defined as 10 cm from anal verge.
According to the literature, leakage rates for low anterior resection (LAR) can range from 8% to approximately 30%.
Schmidt O, Merkel S, Hohenberger W. Eur J Surg Oncol 2003, Taflampas P, Christodoulakis M, Tsiftsis DD. Surg Today 2009, Lim M, Akhtar S, Sasapu K, et al. Dis Colon Rectum 2006, 49(10):1611-9, Akyol AM, McGregor JR, Galloway DJ, et al. Int J Colorectal Dis 1991, JT, Lai HS, Lee PH. Ann Surg Oncol 2007, Brisinda G, Vanella S, Cadeddu F, et al. J Surg Oncol 2009.