Clinical Evidence Highlights

pdfASCRS 2013 poster Intermediate Results of WCCA RETROPRESS Study: Compression Anastomosis Is Associated With a Low Rate of Anastomotic Leakage

pdfRecent Data - Compression Anastomosis for Low Anterior Resection (LAR)

pdfLow Anterior Resection (LAR) Leakage & Mortality: Literature Analysis Compared to COMPRES Results

pdfASCRS 2012 poster COMPRES Final Results: Nitinol Compression Anastomosis Results in a Much Lower Than Expected Rate of Anastomotic Leak in Low Anterior Resection (LAR)

pdfASCRS 2012 poster Histopathological Advantages of Compression Ring Anastomosis Healing Compared to Stapled Anastomosi

Read more about Clinical Evidence

Compression Anastomosis in Colorectal Surgery

Compression Anastomosis in Colorectal Surgery Video

This video shows how compression anastomosis works in colorectal surgery. novoGI's clinically proven nitinol technology works with the biological forces of the healing process. This enables dynamic compression anastomosis of varying tissue thicknesses for natural healing following colorectal surgery. Play video

Intraluminal Diameters – Intraoperative & Postoperative

Intraluminal Diameters – Intraoperative & Postoperative

This video shows intraoperative and postoperative intraluminal diameters for compression anastomosis compared to stapling. Play video

Peer-review Library

Cohen S, Albert M, Dominguez J, Galliano D, Stamos MJ. Compression anastomosis is associated with a low rate of anastomotic leakage: intermediate results of WCCA RETROPRESS study. Poster presented at: Annual Scientific Meeting of the American Society of Colorectal Surgeons (ASCRS); April 28-May 1, 2013; Phoenix, AZ. Abstract P318. pdfView PDF 

Masoomi H, Luo R, Mills S, Carmichael JC, Senagore AJ, Stamos MJ. Compression anastomosis ring device in colorectal anastomosis: a review of 1,180 patients. Am J Surg. 2013 April;205(4):447-451. doi:10.1016/j.amjsurg.2012.03.013. Epub 03 Jan 2013.

Kopelman D, Kopelman A, Peled D, Willenz U, Zmora O, Wasserberg N. Healing of ileocolic nitinol compression anastomosis: a novel porcine model of subtotal colectomy. Surg Innov. Published online ahead of print April 10, 2013. doi:10.1177/1553350613484592..

D'Hoore A, Cohen S, Albert M, Herbst F, Senagore A, Stamos MJ, Pahlman L, Wexner SD. COMPRES final results: nitinol compression anastomosis results in a much lower than expected rate of anastomotic leak in low anterior resection (LAR). Poster presented at: Annual Scientific Meeting of the American Society of Colorectal Surgeons (ASCRS); June 2-6, 2012; San Antonio, TX. pdfView PDF 

Berho M,Fleshman JW, Wexner SD, Anug AM, Pelled D. Histopathological advantages of compression ring anastomosis healing as compared to stapled anastomosis in a porcine model: a blinded comparative study. Poster presented at: Annual Scientific Meeting of the American Society of Colorectal Surgeons (ASCRS); June 2-6, 2012; San Antonio, TX.pdfView PDF

Hatwell C, Lefevre J, Ferron M, Bretagnol F, Panis Y. Compression ring anastomosis in rectal cancer surgery: a prospective study in 26 patients. Colorectal Dis. 2012;14(suppl 2):55. doi: 10.1111/j.1463-1318.2012.03157.

Madoff, RD. The uses of surgical history. Dis Colon Rectum. August 2012;55(8):829-830. doi:10.1097/DCR.0b013e31825d5d7b.

Dauser B, Herbst F. Historisches: Kompressionsanastomosen in der kolorektalen Chirurgie [in German]. Chirurgie. 2012;3:38-41.

Zbar AP, Nir Y, Weizman A, Radau M, Senagore A. Compression anastomosis in colorectal surgery: a review. Tech Coloproctol. 2012 June;16(3):187-199. doi: 10.1007/s10151-012-0825-6.

Kang J, Park MG, Hur H, Min BS, Lee KY, Kim NK. Safety and efficacy of the NiTi shape memory compression anastomosis ring (CAR/ColonRing) for end-to-end compression anastomosis in anterior resection or low anterior resection. Surg Innov 2013 Apr;20(2):164-70. doi: 10.1177/1553350612449073. Epub 13 Jun 2012.

Kim HR, Lee WY, Jung KU, et al. Early surgical outcomes of NiTi endoluminal compression anastomotic clip (NiTi CAC 30) use in patients with gastrointestinal malignancy. J Laparoendosc Adv Surg Tech. 2012 June;22(5):472-478. doi:10.1089/lap.2011.0406.

Grassi N, Cipolla C, Bottino A, et al. Validity of shape memory NiTi colon ring BioDynamix ColonRing (or NiTi CAR 27) to prevent anastomotic colorectal strictures. Preliminary results. G Chir. 2012 May;33(5):194-198. PMID: 22709459.

Li L, Shen J, Wang J. Colorectal anastomosis using nickel titanium compression anastomosis ring: a prospective study. Chin J Dig Surg. 2012 April;11(2):173-176.

Koo EJ, Choi HJ, Woo JH, et al. Anastomosis by use of compression anastomosis ring (CAR™ 27) in laparoscopic surgery for left-sided colonic tumor. Int J Colorectal Dis. 2012 Mar;27(3):391-396. doi: 10.1007/s00384-011-1310-9.

Khromov Y, Pliakos I, Ibrahim M, Zbar AP, Sayfan J, Papavramidi TS. A prospective multi-institutional study assessing clinical outcome with the NiTi compression anastomosis ring (Biodynamix ColonRing™) in elective colorectal anastomoses. Hepato-Gastroenterology. [published online ahead of print 01 May 2013]. doi 10.5754/hge 12014.

Lee HY, Woo JH, Park SY, Kang NW, Park KJ, Choi HJ. Intestinal anastomosis by use of a memory-shaped compression anastomosis clip (Hand CAC 30): early clinical experience. J Korean Soc Coloproctol. 2012;28(2):83-88.

Avgoustou C, Penlidis P, Tsakpini A, Sioros C, Giannousis D. Compression anastomoses in colon and rectal surgery with the NiTi ColonRing™. Tech Coloproctol. 2012;16:29-35.

Dauser B, Winkler T, Loncsar G, Herbst F. Compression anastomosis revisited: prospective audit of short- and medium-term outcomes in 62 rectal anastomoses. World J Surg. 2011 Aug;35(8):1925-1932. doi: 10.1007/s00268-011-1135-2.

Lee JY, Woo JH, Choi HJ, et al. Early experience of the compression anastomosis ring (CAR 27) in left-sided colon resection. World J Gastroenterol. 2011;17(43):4787-4792.

Buchberg BS, Masoomi H, Bergman H, Mills SD, Stamos MJ. The use of a compression device as an alternative to hand-sewn and stapled colorectal anastomoses: Is three a crowd? J Gastrointest Surg. 2011;15(2):304-310.

Avgoustou C, Penlidis P, Sioros Ch, et al. Colon to colon, small bowel to colon and colorectal anastomoses with the compression anastomosis ring NiTi CAR™ 27. Hellenic J Surg. 2011;83(3):126-132.

Li XX, Cai SJ, Gao J, et al. Prospective study on the use of nickel-titanium temperature-dependent memory-shape device (CAR27) for anastomosis after colorectal surgery. Zhonghua Wei Chang Wai Ke Za Zhi(Chin J Gastrointest Surg). 2011;14(5):330-332.

Hua S, Xiong L, Wen Y, et al. Safety and efficacy of gastrointestinal anastomosis with Nickel Titanium compression anastomosis clip. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2011;36(4):351-354.

Hur H, Kim HH, Hyung WJ, et al. Efficacy of NiTi Hand CAC 30 for jejunojejunostomy in gastric cancer surgery: results from a multicenter prospective randomized trial. Gastric Cancer. 2011;14(2):124-129. doi: 10.1007/s10120-011-0010-z.

Chun J, Lee D, Stewart D, Talcott M, Fleshman J. Comparison of the compression anastomosis ring (EndoCAR) with a circular stapled anastomosis in a porcine model. Surg Innovation. 2011 Sep;18(3):235-240. doi: 10.1177/1553350611408388.

Chun J, Parikh P, Lee D, Fleshman J. Safety of the NiTi EndoCAR following chemoradiation in a porcine model. Surg Innovation. 2011 Dec;18(4):394-399. doi: 10.1177/1553350611398879.

Liang JW, Wang Z, Zhang XM, Zhan DW, Zhou ZX. Animal experimental study of compression anastomosis ring for low anterior resection. Zhonghua Wei Chang Wai Ke Za Zhi(Chin J Gastrointest Surg). 2011;14(5):333-335.

Gross, E. The sutureless compression anastomosis CAR 27 in colon and rectum. Results in 46 patients. Presented at: European Society of Coloproctology (ESCP) 5th Scientific & Annual Meeting; September 22-24, 2010; Sorrento, Italy. Abstract 625.

Tulchinsky H, Kashtan H, Rabau M, Wasserberg N. Evaluation of the NiTi shape memory BioDynamix ColonRing in colorectal anastomosis: first in human multi-center study. Int J Colorectal Dis. 2011;25(12):1453-1458.

Shteinberg D, Sroka G, Misharky F, Matter I. Nitinol compression anastomosis ring for restoration of intestinal continuity after recto-sigmoid resections. Poster presented at: 12th World Congress of Endoscopic Surgery and Society of American Gastrointestinal and Endoscopic Surgeons (SAGES); April 14-17, 2010; Landover, MD. Abstract ETP34.

Li XX, Cai SJ, Guan ZQ, Xu Y, Cai GX, Huang LY. Compression anastomosis ring: a novel technique for colorectal anastomosis.  Zhonghua Wei Chang Wai Ke Za Zhi(Chin J Gastrointest Surg). 2010;13(5):330-332.

Weizman A, Monassevitch L, Greenberg K, Millis S, Harari B, Dar I. FE Analysis of nitinol leaf springs used in a compression anastomosis device. J Materials Eng Performance. 2011;20(4-5):646-652.

Ho YH, Ashour, MA. Techniques for colorectal anastomosis. World J Gastroenterol. 2010;16(13):1610-1621.

Zhang D, Zheng C, Song C. A modified method of using laparoscopic compression anastomosis clip for gastrointestinal anastomosis. Minim Invasive Ther Allied Technol. 2010;19(6):350-354.

Dauser B, Herbst F. (2009) NiTi endoluminal compression anastomosis ring (NiTi CAR™ 27):a breakthrough in compression anastomoses? Eur Surg. 2009;41(3): 116–119.

Kopelman Y, Siersema PD, Nir Y, et al. Endoluminal compression clip: full-thickness resection of the mesenteric bowel wall in a porcine model. Gastrointest Endosc. 2009;70(6):1146-1157.

Liu PC, Jiang ZW, Zhu XL, et al. Compression anastomosis clip for gastrointestinal anastomosis. World J Gastroenterol. 2008;14(31):4938-42.

D'Hoore, A, Hompes D, Folkesson J, Penninckx F, Pahlman L. Circular 'superelastic' compression anastomosis: from the animal lab to clinical practice. Minim Invasive Ther Allied Technol. 2008;17(3):172-175.

Chun, JS, Stewart DB, Lee D, et al. Evaluation of the safe and effective performance of the compression anastomosis ring (CAR™) for colorectal anastomosis in comparison to circular stapler in a porcine model. Poster presented at: Annual Scientific Meeting of the American Society of Colorectal Surgeons (ASCRS); 2008.

Kaidar-Person O, Rosenthal RJ, Wexner SD, Szomstein S, Person B.  Compression anastomosis: history and clinical considerations. Am J Surg. 2008;195(6):818-826.

Szold, A. New concepts for a compression anastomosis: superelastic clips and rings. Minim Invasive Ther Allied Technol. 2008;17(3):168-171.

Kopelman D, Szold A, Kopelman Y, et al. Simulation of a colorectal polypoid lesion - a pilot porcine model. Gastrointest Endosc. 2008;67(7):1159-1167.

Tucker ON, Beglaibter N, Rosenthal RJ. Compression anastomosis for Roux-en-Y gastric bypass: observations in a large animal model. Surg Obes Relat Dis. 2008;4(2):115-21.

Li XX, Zheng CZ, Yin K, Cai JL, Rosenthal RJ. Application of laparoscopic compression anastomosis clip for laparoscopic gastrointestinal anastomosis. Zhonghua Wei Chang Wai Ke Za Zhi(Chin J Gastrointest Surg). 2008;11(3):228-30.  

Stewart D, Hunt S, Pierce R, et al. Validation of the NiTi endoluminal compression anastomosis ring (EndoCAR) device and comparison to the traditional circular stapled colorectal anastomosis in a porcine model. Surg Innovation. 2007;14(4):252-260.

Kopelman D, Hatoum OA, Kimmel B, et al. Compression gastrointestinal anastomosis. Expert Rev Med Devices. 2007;4(6):821-828.

Kopelman, D. Compression anastomosis, the optimal hollow viscus anastomosis – are we there yet? Expert Rev Med Devices. 2007;4(4):423-425.

Kopelman D, Lelcuk S, Sayfan J, et al. End-to-end compression anastomosis of the rectum - a pig model. World J Surg. 2007;31(3):532-537.

Szold, A. Nitinol: shape-memory and super-elastic materials in surgery. Surg Endosc. 2006;20(9);1493–1496.

Monassevitch L, BenDov-Laks N, Tyagunov N, et al. Shape memory devices for compression anastomosis in the digestive system. Minim Invasive Ther Allied Technol. 2006;15(2):125.

Nudelman I, Fuko V, Waserberg N, Colonic anastomosis performed with a memory shaped device. Am J Surgery. 2005;190(3):434-438. PMID: 16105532.

Aggarwal R, Darzi A. Compression anastomoses revisited. J AmColl Surg. 2005;201:965-971.

Nudelman IL, Fuko VV, Waserberg N,et al. Colonic anastomosis performed with a memory-shaped device. Am J Surg. 2005;190:434-438.

Song C, Frank T, Cuschieri A. Shape memory alloy clip for compression colonic Anastomosis. J Biomech Eng. 2005;127: 351-354.

Nudelman IL, Fuko VV, Rubin M, Lelcuk S. A nickel titanium memory-shape device for colonic anastomosis in laparoscopic surgery. Surg Endosc. 2004;18:1085-1089.

Nudelman IL, Fuko VV, Rubin M, Lelcuk S. A memory-shape temperature-dependent nickel-titanium device for colonic anastomosis in laparoscopic surgery. Minim Invasive Ther Allied Technol. 2004;13(1):36-41.

Nudelman IL, Fuko VV, Morgenstern S, Greif F, Lelcuk S. Colonic anastomosis with the nickel-titanium temperature dependent memory-shape device. Am J Surg. 2002;183:697-701.

Nudelman IL, Fuko VV, Morgenstern S, Giler S, Lelcuk S. Gastrointestinal anastomosis with the nickel-titanium double ring. World J Surg. 2000;24:874-877.